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Quality of life after out of hospital interventional orthopaedic & regenerative medicine procedures in an integrated service delivery model

Arockia Xavier Doss


Background & Aim: Out of hospital interventional orthopaedic and regenerative medicine (IORM) procedures are a new addition to the subspecialty of interventional radiology. This study aimed to assess health outcomes following IORM procedures in an outpatient integrated service delivery model in clinical practice.

Methods: Retrospective study of all patients who completed the pre- and post-procedure EuroQol 5D5L questionnaire over a 6 month period.

Results: Forty-eight patients (age range=32-89, mean=60.5, median=63.5 years) were eligible. Mean and median pre-treatment EQ5D5L index values of 0.53 and 0.61(range: -0.248 to 0.879, SD: 0.28, 95% CI: [0.45, 0.61]) improved to 0.73 and 0.73 (range: 0.414-1.0; SD: 0.13, 95% CI [0.69, 0.76]) (p < 0.01, Cohen ‘d’ = 0.93) post-treatment. Improvements in ‘no problems’ in each health dimension were: pain (mathematical infinity), mobility (109%), usual activities (137.5%), self- care (56%), anxiety/depression (23.3%). Reductions in ‘any problems’ in each dimension of health were: pain (-14.5%), mobility (-32%), usual activities (-27.5%), self-care (-60.87%), anxiety/depression (-38.8%). Pre-treatment, a strong negative correlation between EQ5D5L index values versus mobility levels (r = -0.67, p < 0.01) and versus usual activities (r = -0.62, p < 0.01) was present. Post-treatment, a strong negative correlation between EQ5D5L index scores versus pain level (r = -0.68, p <0.01) and versus mobility (r = -0.75, p <0.01) was present.

Conclusion: Significant improvements in all health dimensions with a large treatment effect was shown following outpatient IORM procedures in an integrated interventional radiology service delivery model. Improvements in mobility and pain were the most important determinants of health.


Dimensions of health, integrated practice units, integrated service delivery, interventional orthopaedic and regenerative medicine (IORM), interventional radiology, optimal patient outcomes, patient reported outcome measures (PROMs), person-centered healt

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